SUPPLEMENTARY NOTES for Adaptation as a genome-wide autoregulatory principle in the stress response of yeast
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Adaptation as a genome-wide autoregulatory principle in the stress response of yeast.
The gene expression response of yeast to various types of stresses/perturbations shows a common functional and dynamical pattern for the vast majority of genes, characterised by a quick transient peak (affecting primarily short genes) followed by a return to the pre-stimulus level. Kinetically, this process of adaptation following the transient excursion can be modelled using a genome-wide auto...
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